A Fatal Adverse Effect of Barbiturate Coma Therapy: Dyskalemia

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A Fatal Adverse Effect of Barbiturate Coma Therapy: Dyskalemia

The management guideline for traumatic brain injury (TBI) recommends high-dose barbiturate therapy to control increased intracranial pressure refractory to other therapeutic options. High-dose barbiturate therapy, however, may cause many severe side effects; the commonly recognized ones include hypotension, immunosuppression, hepatic dysfunction, renal dysfunction, and prolonged decrease of cor...

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Prolonged Coma in Barbiturate Poisoning

In 1954 the recorded deaths from barbiturate poisoning in England and ^ were 574 and non-fatal cases were assessed as 6,000 (Locket, 1956). In spite of large number of reported cases in the literature, there were few in which coma1 prolonged for more than a week. The Medical Journal of Australia (1934) menti"' a case of ten days' duration, McElligott (1955) cited another of ten days, Shulman^ (...

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Barbiturate Coma: Rebound and Refractory Hyperkalemia

Purpose: To describe a traumatic brain injury patient who experienced profound dyskalemia upon the initiation and cessation of a pentobarbital infusion and propose management options for future patients receiving this intervention. Methods: Case report. Results: Case report. Conclusions: Dyskalemia has become an anticipated side effect of high dose barbiturate infusions in the setting of elevat...

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Life-Threatening Dyskalaemia after Barbiturate Coma Therapy: The Strategy of Management.

Barbiturate coma therapy (BCT) is a treatment option that is used for refractory intracranial hypertension after all other options have been exhausted. Although BCT is a brain protection treatment, it also has several side effects such as hypotension, hepatic dysfunction, renal dysfunction, respiratory complications and electrolyte imbalances. One less concerning but potentially life-threatenin...

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ژورنال

عنوان ژورنال: Korean Journal of Neurotrauma

سال: 2016

ISSN: 2234-8999,2288-2243

DOI: 10.13004/kjnt.2016.12.2.156